SummaryIn the present article it is argued that Pieter de la Court's Political Maxims of the State of Holland presented a remarkably consistent grand strategy for Holland in relation to its Dutch allies and the European powers. I present an outline of this strategy, which was built around the accomplishment and defence of commercial goals; I sketch a historical context that takes into account the general historical shift from tribute-taking agrarian societies towards commercial wealth-generating polities, and also the violent contemporary (...) military and ideological background against which De la Court's strategy stands out; I argue that his strategy can be understood by his use of three basic game theoretic concepts ; and I stress the distinctive character of De la Court's work, by comparing the practical and strategic use of these concepts in the Maxims with the function of the same concepts in the philosophical contract theories of Thomas Hobbes and Benedict de Spinoza. (shrink)

Albert Schweitzer maintained that the idea of "Reverence for Life" came upon him on the Ogowe River as an "unexpected discovery, like a revelation in the midst of intense thought." While Schweitzer made numerous significant contributions to an incredible diversity of fields - medicine, music, biblical studies, philosophy and theology - he regarded Reverence for Life as his greatest contribution and the one by which he most wanted to be remembered. Yet this concept has been the subject of a range (...) of distortions and misunderstandings, both academic and popular. In this book, Ara Barsam provides a new interpretation of Schweitzer's reverence and shows how it emerged from his studies of German philosophy, Indian religions, and his biblical scholarship on Jesus and Paul. By throwing light on the origin and development of Schweitzer's thought, Barsam leads his readers to a closer appreciation of the contribution that reverence makes to current ethical issues. Whereas previous commentators have focused on "reverence for life" as a philosophical ethic located in that tradition, this book demonstrates that it is in fact Schweitzer's theology that provides the hitherto undiscerned foundation for his ethic. Even among those who herald Schweitzer as the one who brought "reverence" to Christianity, there exists a tendency to underemphasize how his thinking also developed from his pivotal encounter with Indian religions. As Barsam shows, it is impossible to grasp the nature and the significance of Barsam's contribution without addressing that link. Life-centered ethics - in the broadest sense - have continued to flourish, yet Schweitzer's pioneering contribution is often overlooked. Not only did he help establish the issue on the moral agenda, but, most significant, he also provided much sought after philosophical and theological foundations. Schweitzer emerges from this critical study of his life and thought as a remarkable individual who should rightfully be regarded as a moral giant of the twentieth-century. (shrink)

Addresses the nature of human religious belief in a series of vignettes and questions that explore humankind's relationship to the divine, from ancient times to the present, in the context of a taxi ride.

This article sets out and comments on the arguments of Binmore 's Natural Justice, and specifically on the empirical hypotheses that underpin his social contract view of the foundations of justice. It argues that Binmore 's dependence on the hypothesis that individuals have purely self-regarding preferences forces him to claim that mutual monitoring of free-riding behavior was sufficiently reliable to enforce cooperation in hunter-gatherer societies, and that this makes it hard to explain why intuitions about justice could have evolved, since (...) in such a society intuitions about justice would have had no adaptive advantage. I argue that it is empirically plausible that human beings display systematic other-regarding preferences. These could be incorporated into Binmore 's general framework in a way that would enrich it and make it more useful for solving practical problems about justice. Key Words: natural justice • fairness • norms • evolution • self-regarding preferences • Rawls • social contract. (shrink)

The case for U.S. health system reform aimed at achieving wider insurance coverage in the population and disciplining the growth of costs is fundamentally a moral case, grounded in two principles: (1) a principle of social justice, the Just Sharing of the costs of illness, and (2) a related principle of fairness, the Prevention of Free‐Riding. These principles generate an argument for universal access to basic care when applied to two existing facts: the phenomenon of “market failure” in health insurance (...) and, in the U.S., the existing legal guarantee of access to emergency care. The principles are widely shared in U.S. moral culture by conservatives and liberals alike. Similarly, across the political spectrum, the fact of market failure is not contested (though it is sometimes ignored), and the guarantee of access to emergency care is rarely challenged. The conclusion generated by the principles is not only that insurance for a basic minimum of care should be mandatory but that the scope of that care should be lean, efficient, and constrained in its cost. -/- . (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 63.3 (2002) 539-545 [Access article in PDF] Lewis White Beck on Reasons and Causes Paul Guyer Essays by Lewis White Beck: Five Decades as a Philosopher. Edited by Predag Cicovacki. Rochester: University of Rochester Press, 1998. Pp. xxxii, 244. This volume reissues twelve previously uncollected pieces by the late Lewis White Beck (1913-1997) and also includes a reminiscence by a former colleague, (...) an introduction by the editor, and a bibliography of Beck's work. Beck was of course the most distinguished American Kant scholar of his time, who made enduring contributions to scholarship with his translations of Kant's writings in moral philosophy, originally published in Critique of Practical Reason and Other Writings in Moral Philosophy (Chicago, 1949); his trenchant articles on the analytic-synthetic distinction from the early 1950s, collected in his Studies in the Philosophy of Kant (Indianapolis, 1965); his unsurpassed A Commentary on Kant's Critique of Practical Reason (Chicago, 1960); his monumental Early German Philosophy: Kant and His Predecessors (Cambridge, Mass., 1969); his various articles on Kant's treatment of causation, collected in Essays on Kant and Hume (New Haven, 1978); and in his independent philosophical work, The Actor and the Spectator (New Haven, 1975). The present volume, edited by a student from Beck's last years at the University of Rochester, where he spent most of his career, includes articles on a variety of subjects published between 1939 and 1984, and it might seem to be little more than an act of piety toward a now departed but still revered teacher. But a core group of these articles are intimately connected with Beck's central scholarly and philosophical concerns and are well worth republication and renewed study.The articles included in the volume are three early pieces on several central issues in the philosophical debates of the time, "The Synoptic Method" (1939), "The Formal Properties of Ethical Wholes" (1941), and "The Principle of Parsimony in Empirical Science" (1943); an early piece on aesthetics, "Judgments [End Page 539] of Meaning in Art" (1944); two pieces on the tensions between causal explanations and rational evaluations of human behavior, "Psychology and the Norms of Knowledge" (1954) and "Conscious and Unconscious Motives" (1966); Beck's 1971 Presidential Address to the Eastern Division of the American Philosophical Association, a skeptical discussion of "Extraterrestrial Intelligent Life"; an overview of philosophies of time, "World Enough, and Time" (1979); a piece on styles of philosophical writing called "Philosophy As Literature" (1980); and then three pieces on Kant, published after the second of Beck's two earlier anthologies of his articles on Kant: "Kant on the Uniformity of Nature" (1981), "Five Concepts of Freedom in Kant" (1987), and "What Have We Learned from Kant?" (1984). With the last paper, the editor departs from the strictly chronological order he has previously employed, presumably in order to end the volume on a suitably general and retrospective note.I will focus my comments on the two systematic papers on psychological explanation and rational evaluation as well as on the first two Kant papers, all of which touch upon the issues that were central to Beck in his philosophically most important works, the 1960 Commentary on Kant's Critique of Practical Reason and the 1975 The Actor and the Spectator, and which point toward what was Beck's leading idea in both his philosophical and interpretative work: it concerns the idea that the causal explanation of human behavior as a subset of natural events and the rational explanation and justification of human actions are two entirely separate perspectives on the same subject-matter that can be rendered compatible only by the thought that each, causal explanation of behavior on the one hand and rational assessment of actions on the other, is only a regulative ideal for our conduct of inquiry and thus that neither represents a metaphysically privileged point of view. This was an approach that Beck claimed to have been foreshadowed in Kant's resolution of the "Antinomy of Teleological Judgment" in his last great critique, the Critique of the Power... (shrink)

We invoke a triple rationale to rebut Hooper and Spicer's argument against mandatory helmet laws. First, we use the laws of physics and empirical studies to show how bicycle helmets afford substantial protection to the user. We show that Hooper and Spicer erroneously downplay helmet utility and that, as a result, their attack on the utilitarian argument for mandatory helmet laws is weakened. Next, we refute their claim that helmet legislation comprises unjustified paternalism. We show the healthcare costs of bareheaded (...) riding to pose significant third party harms. It follows, we argue, that a utilitarian case for helmet laws can be sustained by appeal to Mill's Harm Principle. Finally, we reject Hooper and Spicer's claim that helmet laws unjustly penalise cyclists for their own health-affecting behaviour. Rather, we show their argument to suffer by disanalogy with medical cases where injustice may be more evident, for example, denial of bypass surgery to smokers. We conclude that mandatory helmet laws offer substantial utility and are entirely defensible within the framework of a liberal democracy. (shrink)

The Dalai Lama is fond of quoting a statement in which the Buddha is said to have asserted that no one should accept his word out of respect for the Buddha himself, but only after testing it, analysing it ‘ as a goldsmith analyses gold, through cutting, melting, scraping and rubbing it’. The Dalai Lama is often referred to as the temporal and spiritual leader of Tibet, but in truth as a spiritual figure His Holiness, while respected, indeed revered by (...) almost all Tibetans, usually speaks from within the perspective of one particular tradition of Tibetan Buddhism, that of the dGe lugs . Founded in the late fourteenth century by Tsong kha pa, the dGe lugs has always stressed the importance of reasoning, analytic rationality, on the spiritual path. This dGe lugs perspective is by no means shared by all Buddhists, at least not in the form it there takes. Nevertheless it does represent an important direction in Buddhist thinking on reasoning and the spiritual path which can be traced back in Indian Buddhism a very long way indeed, and it is in the light of dGe lugs thought that I want to contemplate two points which seem to be crucial in Raimundo Panikkar's approach to interreligious dialogue and understanding: first, that Reality, Being, transcends the intelligible, the range of consciousness, and second, that understanding this is the only basis for tolerance, not seeking in one way or another to overcome the other. (shrink)

This authoritative collection surveys the teachings of Confucius, and illustrates his importance throughout Chinese history in one focused and incisive volume. A Concise Companion to Confucius offers a succinct introduction to one of East Asia’s most widely-revered historical figures, providing essential coverage of his legacy at a manageable length. The volume embraces Confucius as philosopher, teacher, politician, and sage, and curates a collection of key perspectives on his life and teachings from a team of distinguished scholars in philosophy, history, religious (...) studies, and the history of art. Taken together, chapters encourage specialists to read across disciplinary boundaries, provide nuanced paths of introduction for students, and engage interested readers who want to expand their understanding of the great Chinese master. Divided into four distinct sections, the Concise Companion depicts a coherent figure of Confucius by examining his diverse representations from antiquity through to the modern world. Readers are guided through the intellectual and cultural influences that helped shape the development of Confucian philosophy and its reception among late imperial literati in medieval China. Later essays consider Confucius’s engagement with topics such as warfare, women, and Western philosophy, which remain fruitful avenues of philosophical inquiry today. The collection concludes by exploring the significance of Confucian thought in East Asia’s contemporary landscape and the major intellectual movements which are reviving and rethinking his work for the twenty-first century. An indispensable resource, A Concise Companion to Confucius blazes an authoritative trail through centuries of scholarship to offer exceptional insight into one of history’s earliest and most influential ancient philosophers. A Concise Companion to Confucius: Provides readers with a broad range of perspectives on the ancient philosopher Traces the significance of Confucius throughout Chinese history—past, present, and future Offers a unique, interdisciplinary overview of Confucianism Curated by a team of distinguished scholars in philosophy, history, religious studies, and the history of art A Concise Companion to Confucius is an ideal text for undergraduate and graduate courses on Confucius and Confucianism. It is also fascinating and informative reading for anyone interested in learning more about one of history’s most influential philosophers. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:I Am Not Sure?Paul E. LevinIt was a beautiful Friday morning, a few weeks into the summer. My schedule appeared lighter than usual and I even envisioned leaving work a bit early. Maybe a challenging bike ride before dinner. I was sitting in the chairman’s office having our weekly meeting. One of our junior faculty members called... he needed help. He was on call and a 32–year–old (...) pregnant woman with a displaced femoral neck fracture had just been transferred to our emergency department (ED). Ms. B tripped in her kitchen last evening. She was unable to stand and was brought to the local ED by ambulance.My colleague was concerned that he wouldn’t be able to successfully reduce the fracture. The long–term prognosis of the hip joint depended on a successful reduction of the femoral neck fracture. In addition, there was an ongoing debate in the orthopaedic literature related to the urgency of operative care to prevent osteonecrosis of the femoral head. I reviewed the x–rays, didn’t anticipate a problem and let him know that I would come to the operating room (OR) to assist. “No”, he responded, “I am not comfortable caring for this patient”. I immediately left the office, went to the hospital and assumed care of the patient. Clearly, my plans for a bike ride were gone, but I had the opportunity to help a woman in need of expert orthopaedic care.Ms. B had been admitted to the obstetrical service. She was a 32–year–old woman of Haitian descent who had recently immigrated to the United States. She had very limited English comprehension and her primary spoken languages were French and Creole. She was alone, in a hospital in a foreign country. She was 24 weeks pregnant with her first child and had no other co–morbidities. Her pregnancy had ben progressing uneventfully.When I first met Ms. B she was lying on a stretcher in an observation unit on the obstetrical floor. She appeared frightened. Two orthopaedic residents were present and obtaining consent for surgical repair of the hip. In their minds there was nothing to discuss, the patient had a displaced femoral neck fracture and needed to have surgery immediately. In their minds, no other options were available and obtaining consent would be straightforward. I introduced myself, sat down on a lab stool by the bed and began a conversation. I needed to meet the patient, understand who she was and discuss treatment. I am not sure that obtaining an informed consent is ever “straightforward” when [End Page 14] a doctor is explaining to a patient that they require emergency surgery. This discussion surely would not be easy or straightforward.We utilized a telephone interpretation service. Every question and response required the transfer of the handset between the patient and physician. Ms. B was in pain and frightened. She immediately expressed concern about her pregnancy and her baby. I arranged for her to meet all of the physicians who would possibly be involved in her care and the care of her baby. Each consultant could explain their area of expertise and potential involvement in the care of Ms. B and her child. She met and had an opportunity to talk with the obstetrician on call, a maternal fetal medicine (MFM) fellow and a neonatologist. I supplied the orthopaedic information. I explained the severity of the injury, the risks of osteonecrosis either with or without surgery as well as concerns over non–union and traumatic arthritis of the hip. Undoubtedly, in a healthy 32–year–old woman who wasn’t pregnant, early surgical intervention would be the most appropriate management in hopes of preserving a normal hip joint. We also discussed the possibility of treating her without surgery. She would be administered pain medication, which were known to be safe during pregnancy, and allowed to begin to ambulate with a walker or crutches. I explained potential problems without surgery and what options would be available to treat any problems that developed with her hip after the child was born. Of course, hip fractures in pregnant woman are very rare, and as a result treating a... (shrink)

Nietzsches Philosophie ist ein hermeneutische. H.-G. Gadamer kennzeichnet die hermeneutik als ein parktische Philosophie. In diesem Aufsatz wird versucht Nietzsches Bedeutung für ein Hermeneutik als parktische Philosophie zu skizzieren an Hand einer Behandlung des Themas 'Scham' in seinen Schriften. Im ersten Teil wird die Entwicklung von Nietzsches Gebrauch des Begriffs 'Scham' verfolgt. im zweiten Teil werden die Ergbnisse gesammelt in einer Beschreibung von Nietzsches 'Hermenuetik der Scham'. Scham ist ein Form des praktischen Vorveständnis der Welt. Der Philosoph muss, Nietzsche zufolge, (...) einerseits 'schamlos unerschocken' sein, wird andererseits aber gekennzeichnet durch, 'Ehfurcht, Scham und Teif'. Zum Schluss wird den Underschied zwischen dieser und die gadamersche Hermeneutik angedeuter.Nietzsche's philosophy is hermeneutical. Hermeneutics is according to H.-G. Gadamer: practical philosophy. The article tries to explain Nietzsche's contribution to a hermeneutics as practical philosophy, by way of a discussion of the meaning of "shame" in his writings. In the first part the development of the concept of shame in Nietzsche's writings is outlined in four stages. In the second part the results of this overview are collected in a description of Nietzsche's hermenuetics of shame: shame is part of our practical preunderstanding of the world. The philosopher has, according to Nietzsche, to be 'fearlessly shameless' on the one hand, but is characterised by 'modesty [Scham] and delicate reverence' on the other. Hermeneutical consciousness can be characterised in terms of shame. (shrink)

This first-rate collection of essays in French stems from several international colloquia organized by a joint research program on utopia and catastrophe at the universities of Bordeaux-Montaigne and Poitiers between 2011 and 2013. Globally, as the title of Jean-Paul Engélibert and Raphaelle Guidée's excellent introduction makes immediately clear, the volume questions and refutes the depreciation of utopia expressed frequently in the last decades: the contemporary propensity to point, if not to the death of utopia, to the flourishing of dystopias (...) since the nineteenth century and the view that utopias themselves are the root cause of most twentieth-century crises and... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Scars of the Spirit: The Struggle Against InauthenticityChristopher S. SchreinerScars of the Spirit: The Struggle Against Inauthenticity, by Geoffrey Hartman; xii & 260 pp. New York: Palgrave Macmillan, 2002. $17.95 paper.Geoffrey Hartman is now an emeritus faculty member at Yale. All but the youngest readers of this journal will recognize him as a member of the now defunct Yale School of Criticism, which in its glory days included (...) Harold Bloom, Hillis Miller, Paul de Man, and Jacques Derrida. Among these accomplished individuals, Hartman distinguished himself as the one most engaged with discussing the role of style in theoretically propelled criticism, and this remains his lasting contribution. The question he kept asking was the following: what demands do the books we read and the theories we use make on our own critical practice, and in particular, on our style? Works such as Criticism in the Wilderness (1980) and Saving the Text (1981) were concerned with promoting a philosophical criticism that is as creative as the literature it seeks to criticize, in opposition to the Arnoldian standard of a disinterested criticism that respects and preserves the canonical hauteur of literary classics and doesn't seek to imitate them. Yet over the decades Hartman's own prose, except when it lapsed into copying Derrida's, seemed more that of the Doctor and less the Explorer, to borrow the terms Lionel Trilling used to describe Matthew Arnold's criticism. This is an irony we are grateful for.Hartman's most recent book, Scars of the Spirit, takes up the problem of authenticity in the context of postmodern culture, seeking to reestablish its legitimacy as a serious topic and unmask what merely poses as authentic in the global marketplace. Today his agenda ignominiously crosses paths with the likes of Jane Fonda, whose autobiography is replete with New Age claims to recover "the authentic me." One of the issues never resolved by Hartman's book and which taunts his project behind its back is whether his Continental erudition makes his project any more authentic than Fonda's celebrity psychobabble. Authenticity was the Heideggerian concept that Adorno ruthlessly and ironically attacked in his The Jargon of Authenticity, and it has an old-fashioned existential ring to it to this day. For those readers who haven't read Being and Time lately, authenticity (Jemeinigkeit) was the resolute impetus of making time one's own, taking it back from the instrumental public world that had appropriated it so that one can live a sincerely mortal life and die one's own death, as it were properly. Professors valiantly conjured an ethic out of this retrieval of selfhood, of one's personal property of time and destiny in the Lost and Found of culture, not fully cognizant of its Nietzschean roots. The absence of altruism in this existential ethic inspired Emmanel Levinas's patient attempt to persuade us to demote our egoism in an insatiable responsibility to and for others, for whom we can never do enough.There is surely irony in the fact that the anachrony of authenticity as a concept was accelerated by the deconstructive theory that Hartman helped [End Page 501] promulgate. Hence his new book reads a bit like someone having to gingerly retrace his steps in a field of landmines planted by the Yale School of Criticism. The question of propriety, what is right and proper, what is one's own, stamped with one's unique or authentic properties, was deconstructed by Derrida, and Hartman reverently recorded the results in the incongruously titled Saving the Text, an analysis of Derrida's attempt to promote textual intercourse between Hegel and Jean Genet by setting them in parallel columns on one page. In a nutshell, the original source of an event or text, its material advent, is untraceable due to its derivativeness, the forces of semiosis (or textuality) at play in and between texts. In parallel to this discovery, Jean Baudrillard spoke of the simulacrum as a media-generated version behind which the original "thing itself" was forever irrecoverable. The very idea of authenticity came to sound illusory, denoting a mirage sought in a hopeless regressive inquiry or Ruckfrage which Husserl (with... (shrink)

In a well-known apocryphal story, Theresa of Avila falls off the donkey she was riding, straight into mud, and injures herself. In response, she seems to blame God for her fall. A playful if indignant back and forth ensues. But this is puzzling. Theresa should never think that God is blameworthy. Why? Apparently, one cannot blame what one worships. For to worship something is to show it a kind of reverence, respect, or adoration. To worship is, at least in part, (...) to praise. You cannot praise and blame simultaneously. Indeed, Paul counsels against “back-talk” against God, suggesting we lack the standing to blame our creator (Romans 9:20). Drawing on Strawsonian theorizing about praise and blame, this paper argues that, surprisingly, a person can both blame and worship God. Although blameful worship is possibly epistemically akratic, it may sometimes be acceptable given our nature as finite, emotional beings. In fact, blaming God might on occasion be the only way we have to stand with God’s goodness despite apparent evidence of evil in the world. This suggestion, I’ll argue, should change the way we think about the problem of evil. The problem has interpersonal and moral psychological dimensions that merit serious attention. (shrink)

This article extends Aron Gurwitsch’s ( 1964 ) central insight about the field of consciousness—that it is always organized in a theme, thematic field, margin pattern—to the human capacity for reverence. It offers an original phenomenology of reverent awe, inspired by Gurwitsch’s work, as an articulation of reverential index and reverential attitude. According to Paul Woodruff ( 2014 ) in Reverence: Renewing a Forgotten Virtue, reverence names those times when we become aware of something larger than human and simultaneously (...) our human limitations. By bridging the concepts of reverence from Woodruff and relevancy from Gurwitsch, this study shows that in reverent awe the emphasis in consciousness shifts to the edge of relevancy, the zones farthest removed from the theme, as the “indefinite continuation of context,” “order of existence,” or what Gurwitsch also calls an “inarticulate mass”. Reverent awe is clarified phenomenologically as an emphasis in consciousness between the theme and the order of existence as indefinite continuation of thematic context, maintaining a specific relevancy-principle (a Gestalt-connection) between the theme and the order of existence. In a reverential attitude with a reverential index we become aware more immediately of an order of existence and we become aware of our place in the order of existence. (shrink)

According to philosopher Paul Woodruff, reverent awe is a feeling of being limited or dwarfed by something larger than the human, usually accompanied by feelings of respect for fellow human beings. Drawing from Jean-Paul Sartre’s early philosophy, this article responds positively to the title question, showing how reverent awe is in bad faith yet is similar to anguish, and unique with respect to both. Especially remarkable in reverent awe is the feeling of connectedness to humankind. In section two, (...) building on this section one framework of how Sartrean consciousness can be reverent, the article explores how being-in-itself can be an object of reverent awe. (shrink)

Historically, there has been widespread acceptance of the claim that religious belief – and, in particular, theistic belief – is essential to human flourishing, both for human individuals and for human societies. With the relatively recent rise of prosperous secular democracies, it is possible to put this claim to empirical test. When we do, we find no support for the claim that theistic belief is essential to human flourishing, and significant support for the claim that theistic belief impacts negatively on (...) human flourishing. (shrink)

Animal rights campaigners and scientists working with animals completed anonymous questionnaires in which they were asked to report, not only on their own beliefs and ideas about the animal experimentation debate, but also on those they perceived the opposing group to hold. Both groups of participants tended to have a negative and somewhat extreme view of the other. But they did have an accurate grasp of the arguments and defenses commonly offered on both sides of the debate, and showed some (...) agreement concerning the relative capacity of different animals to suffer. Differences appeared in the level of the phylogenetic hierarchy at which participants thought animals might be capable of suffering, and in their decision-making processes regarding the admissibility of animal experiments. (shrink)

The hypothesis that high levels of religiosity are partly caused by high disease loads is in accord with studies showing that societal dysfunction promotes mass supernaturalism. However, some cultures suffering from high rates of disease and other socioeconomic dysfunction exhibit low levels of popular religiosity. At this point, it appears that religion is hard pressed to thrive in healthy societies, but poor conditions do not always make religion popular, either.

Understanding the functional mechanisms underlying genetic signals associated with complex traits and common diseases, such as cancer, diabetes and Alzheimer's disease, is a formidable challenge. Many genetic signals discovered through genome‐wide association studies map to non‐protein coding sequences, where their molecular consequences are difficult to evaluate. This article summarizes concepts for the systematic interpretation of non‐coding genetic signals using genome annotation data sets in different cellular systems. We outline strategies for the global analysis of multiple association intervals and the in‐depth (...) molecular investigation of individual intervals. We highlight experimental techniques to validate candidate (potential causal) regulatory variants, with a focus on novel genome‐editing techniques including CRISPR/Cas9. These approaches are also applicable to low‐frequency and rare variants, which have become increasingly important in genomic studies of complex traits and diseases. There is a pressing need to translate genetic signals into biological mechanisms, leading to prognostic, diagnostic and therapeutic advances. (shrink)

High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated through the p4n channel of this reaction, was also populated to spin similar to 38 (h) over bar and excitation energy 18 MeV. Cranking calculations indicate that (...) these nuclei are soft with respect to the triaxiality parameter gamma and that several competing nuclear shapes occur at high spin. (shrink)

Aristotle's modal syllogistic has been an object of study ever since the time of Theophrastus; but these studies have been somewhat desultory. Remarkably, in the 1990s several new lines of research have appeared, with series of original publications by Fred Johnson, Richard Patterson and Ulrich Nortmann. Johnson presented for the first time a formal semantics adequate to a de re reading of the apodeictic syllogistic; this was based on a simple intuition linking the modal syllogistic to Aristotelian metaphysics. Nortmann developed (...) an ingenious de dicto analysis. Patterson articulated the links between the modal syllogistic and the metaphysics, using an analysis which strictly speaking is neither de re nor de dicto. My own studies in this field date from 1976, when my colleague Peter Roeper and I jointly wrote a paper "Aristotle's apodeictic syllogisms" for the XXIInd History of Logic Conference in Krakow. This paper contained the disjunctive reading of particular affirmative apodeictic propositions, which I still favour. Nonetheless, I did not consider that paper's results decisive or comprehensive enough to publish, and my 1981 book The Syllogism contained no treatment of the modal syllogism. The paper's ideas lay dormant till 1989, when I read Johnson's and Patterson's initial articles. I began publishing on the topic in 1991. Gradually my thoughts acquired a certain comprehensiveness and systematicity, till in 1993 I was able to take a semester's sabbatical to write up a draft of this book. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ritual and Reverence in Ancient China and TodayStephen C. AngleReverence: Renewing a Forgotten Virtue. By Paul Woodruff. Oxford and New York: Oxford University Press, 2001. Pp. 248.It is a sad commonplace that works in moral philosophy rarely do much to make their readers more moral. Unusually gifted classroom teachers can sometimes make a difference in students' lives, though, and now and again there appears a piece of philosophical (...) writing that makes a similar impact. Paul Woodruff has written an extraordinary book that has a chance of joining this select company. Reverence: Renewing a Forgotten Virtue wears its scholarship and philosophy lightly; in addition to lucid exposition and argument, it employs anecdotes, readings of a range of poems, and in one chapter a question-and-answer format in order to engage readers in the very real, very contemporary concerns that motivate the book. Woodruff believes that we have largely forgotten how to talk about reverence, even though its practice has not disappeared, so his sources for the theory of reverence are largely ancient-both Greek (his specialty) and Chinese. He weaves together classical text and contemporary issue in masterful fashion, producing a book that is both philosophically challenging and potentially transformative. I will comment mainly on its philosophical themes, but I urge one and all to experience the book's power.Reverence, says Woodruff, is a virtue: indeed, one of the most important of virtues. It is the "well-developed capacity to have the feelings of awe, respect, and shame when these are the right feelings to have" (p. 8). He characterizes the "belief in human imperfection" as the "central belief of reverence" (p. 199), and this makes sense, even though reverence is not primarily about beliefs. The idea that we are limited or imperfect informs each of the three feelings through which reverence is expressed. It is easy to see how this works with awe, but respect and shame are more complicated, requiring further discussion below. Woodruff offers the following initial formulation of the interrelationship among the three:Reverence begins in a deep understanding of human limitations; from this grows the capacity to be in awe of whatever we believe to be outside our control—God, truth, justice, nature, even death. The capacity for awe, as it grows, brings with it the capacity for respecting human beings, flaws and all. This in turn fosters the ability to be ashamed when we show moral flaws exceeding the normal human allotment,(p. 3)He continues by saying that this syndrome was recognized by the Greeks before Plato, and that "the immediate followers of Confucius thought much the same." [End Page 471]Woodruff's tying of reverence to specific thinkers immediately makes one wonder what word or words he is translating as reverence, if it was known in Greece and China. Comparative philosophers will also ponder the words "much the same": is there really a single virtue called "reverence" that, without our previously realizing it, can be found in both the Greek and Chinese traditions? Or are there two, more loosely related, ideas?Woodruff's answer is that there is a single virtue, but that it is realized and theorized somewhat differently in different contexts. Indeed, he does not insist that the concept of reverence that he finds in ancient Confucianism is the only Confucian concept of reverence. He relies only on the Analects and Mencius as sources, and readily acknowledges that his picture is partial and simplified (p. 230). He makes similar qualifications with respect to his Greek sources. His "reverence," then, is in the first instance a rational reconstruction built upon the ideas/terms of different traditions as well as his own philosophical reasoning. In the Greek case, he says that the concept he is exploring is "named both by hosiotēs and its near synonym eusebia, which is frequently translated as 'piety'" (pp. 225-226). Once we know this, it is easy to see that his topic was discussed in Greek texts and to ask how these texts fit the awe-respect-shame schema he has identified.Rather than pursue this topic—on which see particularly Woodruff's chapter 5—I am going to spend some time... (shrink)

A letter replying to Bayne et al. "Tests for consciousness in humans and beyond", 2024, arguing that the search for consciousness "beyond" healthy adult humans should begin with other animals.

The Theaetetus is one of the most widely studied of any of the Platonic dialogues because its dominant theme concerns the significant philosophical question, what is knowledge? In this book Paul Stern provides a full-length treatment of its political character in relationship to this dominant theme. He argues that this approach sheds significant light on the distinctiveness of the Socratic way of life, with respect to both its initial justification and its ultimate character. More specifically, he argues that Socrates' (...) revolutionary decision to subject political life to philosophic reflection, the decision that leads directly to his trial and execution, is based on his awareness of the elusiveness of comprehensive knowledge and the implications of that elusiveness for the validity of philosophic inquiry. This view of Socrates' rationale has important consequences for our understanding of political philosophy and of the validity of the life of reason itself. (shrink)

Hegel makes claims about the relation of philosophy to religion that might raise concerns for those who want to locate his philosophy generally within the modern enlightenment tradition. For example, at the outset of his Lectures on Aesthetics he claims that philosophy “has no other object but God and so is essentially rational theology”.1 What might seem to placate worries here is that Hegel of course differentiates between the forms of religious and philosophical cognition in which such a content is (...) presented: while religion grasps this content in the form of imagistic or figurative representations [Vorstellungen], philosophy grasps it within conceptual thought, an attitude which might seem to align him with that found within the German enlightenment, for example, that found in Lessing and Kant. However, it seems undeniable that, in comparison to Kant, for example, Hegel employs forms of expression for the presentation of his own philosophical thought that are redolent with the type of imagistic and figurative locutions supposedly at home in religion. Moreover, the actual imagery employed seems to refer to the type of trinitarian version of Christianity that can seem antithetical to those forms of Christian thought that lent themselves to the sort of “demythologization” characteristic of the enlightenment attitude to religious doctrine. Such factors as these make it easy to portray Hegel’s philosophy as a type of irrationalist mysticism,2 or at least as a disguised theology with a content from revealed religion, and thus aligning him more to the spirit of the Counter-Enlightenment than the Enlightenment. (shrink)

Because of Paul’s egalitarianism evidenced in his concern for an inclusive salvation that did not discriminate against gentiles, it is widely assumed that Paul opposed all ethnic distinctions as contrary to the message of Christ. A close look at his letters, especially the letter to the Romans, shows that whilst Paul, because of his belief in the impartiality of God, argues against discrimination, he does differentiate clearly between Jew and Greek and does not oppose ethnic distinctions as (...) such. What Paul opposes is the hostility that emerges from a failure to recognize and accept the other in their distinctive identity. He is thus an advocate of social and cultural diversity rather than of uniformity. (shrink)

This companion to Elliot Dorff's three books on Jewish ethics -- Matters of Life and Death , To Do the Right and the Good , and Love Your Neighbor and Yourself -- is designed for group as well as individual study. Through suggested readings from Dorff's books, probing questions, lively discussion topics, and simple writing exercises, readers will be able to analyze and clarify their own positions on a host of controversial issues: sex, surrogate motherhood, adoption, family abuse, responsibilities for (...) charitable giving, the ethics of war, suicide, and euthanasia, and more. (shrink)

This study examined the historical perspectives of eleven emergent bilingual and bilingual students at two middle schools. Data analysis revealed that the participants’ perspectives on U.S. history reflected three schematic narrative templates focused on nation-building, equality, and discrimination. The participants primarily employed the (in)equality narratives when discussing aspects of U.S. history directly linked to their identities. The findings add to the extant research on student historical perspectives and use of schematic narrative templates. The findings further suggest that engaging (emergent) bilingual (...) students in examining multiple perspectives and conducting critical history inquiry can contribute to notions of culturally and linguistically responsive social studies instruction. (shrink)